11)  Which of the following method is used to manufacture suppositories

a)    Hard molding
b)    Compression molding
c)    Pour molding

12)  Which of the following is most commonly used suppository base

a)Cocoa butter
c)    PEG + Hexanetriol
d)    None

13)  Cocoa butter available in following forms

a) alpha form
b) beta form
c) gamma form
d) all of these

14)  The solidification point of cocoa butter lies between (degree centigrade)

a)    12 – 13
b)    20 – 30
c)    5 – 10
d)    None

15)  Which of the following method is simple & oldest method of preparation of suppositories?

a)    Hand molding
b)    Compression molding
c)    Pour molding
d)    All the above

16)  Most commonly used method for producing suppositories on both a small & large scale is

a)    Hand molding
b)    Compression molding
c)    Pour molding
d)    All the above

17)  Which formula can be used to calculate the amount of base that is replaced by active ingredients?



18)  Rancidity generally results from

a)    Auto oxidation
b)    Decomposition of unsaturated fats
c)    Both
d)    None

19)  Which of the following is not antioxidant

a)    BHT
b)    BHA
c)    Tocopherol
d)  Theobroma oil

20)  Suppositories are generally evaluated by

a)    Melting range test
b)    Breaking test
c)    Liquefaction
d)   All the above

.Suppository base is that it should remain ____ at room temperature.
a)solid
b)liquid
c)gaseous
d)semi solid
2..Suppository base should _ at body temperature.
a)soften
b)melt
c)dissolve
d)all of these
3.The base must be capable of _ to release its drug for absorption.
a)softening
b)melting
c)dissolving
d)all of these
4.If the base interacts with the drug to inhibit its release, drug absorption will be impaired or even prevented.
a)true
b)false
5.Slow-release suppositories contain
a)alginic acid
b)acetic acid
c)citric acid
d)all of these
6.Which of the following is not an ideal property of bases?
a)It must retain the shape and size
b)It should shrink sufficiently to remove from mould
c)It should be compatible with variety of drugs
d)It should soften or harden on storage
7.Suppository bases are classified as
a)Fatty or Oily Bases or Oleaginous bases
b)Water Soluble & Water miscible bases Or Hydrophilic bases
c)Emulsifying/Synthetic bases
d)All of these
8.Which of the following is/are Oleaginous bases?
a)Theobroma Oil
b)Glycero-gelatin base
c)Massa estarinum
d)All of these
9.Cocoa butter is fat obtained from
a)stem of Theobroma cocoa
b)roasted seed of Theobroma cocoa
c)roasted leaves of Theobroma cocoa
d)all of these
10.Cocoa butter melts at
a)20 – 25 degrees
b)30 – 35 degrees
c)above 40 degrees
d)below 20 degrees

11.Disadvantages of Cocoa butter is/are
a)Rancidity
b)Stick to mould
c)Costly
d)All of these
12.Which of the following are Hydrogenated oils?
a)coconut oil
b)stearic acids
c)palm kernel oil
d)all of these
13.Polyethylene glycol is which type of suppository base?
a)Fatty or Oily Bases or Oleaginous bases
b)Water Soluble & Water miscible bases Or Hydrophilic bases
c)Emulsifying/Synthetic bases
d)All of these
14.Polyethylene glycol is also known as
a)Witepsol
b)Massa estarinum
c)Macrogol
d)All of these
15.Witepsol is classified as which type of suppository base?
a)Fatty or Oily Bases or Oleaginous bases
b)Water Soluble & Water miscible bases Or Hydrophilic bases
c)Emulsifying/Synthetic bases
d)All of these