All Antibiotics according to the mechanism of action

متى نفضل إعطاء مضاد حيوي واسع الطيف ؟
في الحقيقه يفضل إعطاء مضاد واسع الطيف في حالتين وليس أي انفكشن يعطى
الحاله الأولى عندما يكون هناك
mixed infections where multiple organisms are likely to be present.
مثل
intra-abdominal and female pelvic infections
في هذه الحاله قد يصاب ب
aerobic and anaerobic bacteria
في هذه الحاله ي أما نجيب دواء واسع الطيف يغطي النوعين او نضيف دوائين.
الحالة الثانيه في
critically ill patients with presumed healthcare-associated infections
وهذا بسبب انة غالبا يصاب ب
multi-drug resistant.

Septic shock definition and fluid resuscitation

Vassopressors drugs in septic shock

Assessment of Tissue perfusion in septic shocks patient

السودان في غياهب الحرب و النسيان
..
نسأل الله ان يفرج عنهم ويرفع عنهم الحرب ويرحم شهاداتهم

Antimicrobial in Septic shock

Corticosteroid and sodium bicarbonate in septic shock

🔹PCT appears to be a more specific marker for bacterial infections than either CRP or ESR, and it can be a valuable tool for the clinician to help assess mortality risks of patients with infections and also can help determine when to initiate antibacterial

nutrition in septic shock
اخر موضوع

✅خلصت اجازة العيد والحمدلله اني اقدرت احضر وسجل موضوعين وهو Community-acquired pneumonia و Septic shock اخذت مني جهد ووقت واكتشفت انه الجانب الأكاديمي متعب😅 اتمنى بانة قد اوصلت الموضوعين بشكل جيد ، وغدا نعود لدوام العمل 😁 ونلتقي في الإجازات في مواضيع ثانية ان شاءالله،أسأل الله أن يكون هذا العمل خالص لوجهه الكريم 👏👏

🔺PCT levels may help determine whether to discontinue empiric antibiotics in possibly infected patients as well as to determine when antibiotics can be discontinued in patients recovering from infections.

🔹PCT levels below 0.25 ng/mL (mcg/L) are associated with low risk of infection and can help justify the discontinuation of antibiotics, while levels >0.5 ng/mL (mcg/L) may indicate that antibiotics should be continued

🛑Approach for shock management

✅Point of care ultrasound to differentiate cause of shock

✅Is there evidence of overt fluid/blood loss e.g. GIT bleeding ➡️blood and fluid resuscitation

✅In absence of evidence of overt blood loss➡️ Fluid responsiveness

✅Titrate norepinephrine to reach MAP ≥ 65 mmHg

✅After reaching the target of MAP ➡️assess tissue perfusion using lactate and/or capillary rfill time

✅If tissue perfusion is adequate→start weaning of vasopressor

✅If tissue perfusion is inadequate consider higher MAP (70-75 mmHg)

✅If tissue perfusion remains inadequate after achieving high MAP→ consider inotropic support in patients with poor contractility.

#Evidence-Based Critical Care Protocols 2022

🛑ادويه anticoagulants المستخدمه في معالجة مريض Acute coronary syndrome هي
✅heparin
✅enoxaparin
✅fondaparinux
✅bivalirudin
السؤال متى نستخدم كل واحد ؟؟