Clinical factors associated with successful antiseizure medication withdrawal
🛑Hypomagnesemia in crtical care patients
✅ Mg deficiency has been reported in 50% of patients receiving chronic therapy with furosemide
✅hypomagnesemia has been reported in 30% of patients receiving aminoglycoside therapy
✅Hypomagnesemia is reported in as many as 80% of patients with acute myocardial infarction.,The mechanism is unclear, but may be due to an intracellular shift of Mg from excess catecholamines.
✅Hypomagnesemia is reported in only 7% of admissions for diabetic ketoacidosis, but the incidence increases to 50% over the first 12 hours after admission , probably as a result of insulin-induced movement of Mg into cells.
✅Hypomagnesemia is reported in as many as 65% of ICU patients , and the incidence of Mg depletion is even higher (because the serumMg level can be normal in patients with Mg deficiency
✅Only 67% of the Mg in plasma is in the ionized (active) form, and the remaining 33% is either bound to plasma proteins or chelated with divalent anions such as phosphate and sulfate
#The Little ICU Book
✅ Mg deficiency has been reported in 50% of patients receiving chronic therapy with furosemide
✅hypomagnesemia has been reported in 30% of patients receiving aminoglycoside therapy
✅Hypomagnesemia is reported in as many as 80% of patients with acute myocardial infarction.,The mechanism is unclear, but may be due to an intracellular shift of Mg from excess catecholamines.
✅Hypomagnesemia is reported in only 7% of admissions for diabetic ketoacidosis, but the incidence increases to 50% over the first 12 hours after admission , probably as a result of insulin-induced movement of Mg into cells.
✅Hypomagnesemia is reported in as many as 65% of ICU patients , and the incidence of Mg depletion is even higher (because the serumMg level can be normal in patients with Mg deficiency
✅Only 67% of the Mg in plasma is in the ionized (active) form, and the remaining 33% is either bound to plasma proteins or chelated with divalent anions such as phosphate and sulfate
#The Little ICU Book
Forwarded from Abdullah Mohamed
Marinos The Little ICU Book.pdf
22.7 MB
🛑 diuretic in decompensated heart failure
✅The presence of pulmonary edema in acute heart failure is NOT evidence of excess extracellular volume, and could be the result of an acute increase in PAWP from diastolic dysfunction (as seen in the “flash pulmonary edema” produced by ischemic myocardial “stunning”).
✅ diuretic therapy with intravenous furosemide should only be used when there is evidence of hypervolemia (such as recent weight gain or peripheral edema), or when the PAWP remains elevated (> 20 mm Hg) despite vasodilator or inodilator therapy.
✅Furthermore, intravenous furosemide should never be used alone in the treatment of heart failure associated with a low cardiac output, and should always be combined with vasodilator or inodilator therapy.
✅ Intravenous furosemide produces an acute vasoconstrictor response by stimulating renin release and promoting the formation of angiotensin II, a potent vasoconstrictor
✅ Because this response is counterproductive in the setting of hypertension, furosemide administration should be delayed until the blood pressure is controlled with vasodilator therapy
#Marinos ICU book
✅The presence of pulmonary edema in acute heart failure is NOT evidence of excess extracellular volume, and could be the result of an acute increase in PAWP from diastolic dysfunction (as seen in the “flash pulmonary edema” produced by ischemic myocardial “stunning”).
✅ diuretic therapy with intravenous furosemide should only be used when there is evidence of hypervolemia (such as recent weight gain or peripheral edema), or when the PAWP remains elevated (> 20 mm Hg) despite vasodilator or inodilator therapy.
✅Furthermore, intravenous furosemide should never be used alone in the treatment of heart failure associated with a low cardiac output, and should always be combined with vasodilator or inodilator therapy.
✅ Intravenous furosemide produces an acute vasoconstrictor response by stimulating renin release and promoting the formation of angiotensin II, a potent vasoconstrictor
✅ Because this response is counterproductive in the setting of hypertension, furosemide administration should be delayed until the blood pressure is controlled with vasodilator therapy
#Marinos ICU book
Clinical Notes
🛑 diuretic in decompensated heart failure ✅The presence of pulmonary edema in acute heart failure is NOT evidence of excess extracellular volume, and could be the result of an acute increase in PAWP from diastolic dysfunction (as seen in the “flash pulmonary…
✅ عشان كذا مانستخدم Lasix بمجرد انه مريض decompensate heart failure
✅الخلاصه ممكن نستخدمه لو في علامات على hypervolemia مثل زياده في الوزن بشكل مفاجئ او وجود peripheral edema
او كان pulmonary wedge pressure فوق 20mm Hg ع الرغم من استخدام النتروجلسيرين
✅الخلاصه ممكن نستخدمه لو في علامات على hypervolemia مثل زياده في الوزن بشكل مفاجئ او وجود peripheral edema
او كان pulmonary wedge pressure فوق 20mm Hg ع الرغم من استخدام النتروجلسيرين
🛑 treatment cardiogenic shock ( cold and wet)
✅ if MAP> 100mmHg
Nitroglycerin and diuretics
⛔️if MAP 70_100mmHg and no signs of Shock ( end organ damage)
✅vasodilators
✅ dobutamine
✅diuretic
✅If signs of end organ damage – need vasopressor Norepinephrine (preferred in cardiogenic shock for most patient)
⛔️If MAP <70 mm Hg
✅Vasopressor Norepinephrine (preferred in cardiogenetic shock for most patient)
#American Society of Health-System Pharmacists,
✅ if MAP> 100mmHg
Nitroglycerin and diuretics
⛔️if MAP 70_100mmHg and no signs of Shock ( end organ damage)
✅vasodilators
✅ dobutamine
✅diuretic
✅If signs of end organ damage – need vasopressor Norepinephrine (preferred in cardiogenic shock for most patient)
⛔️If MAP <70 mm Hg
✅Vasopressor Norepinephrine (preferred in cardiogenetic shock for most patient)
#American Society of Health-System Pharmacists,
🛑β‐blockade in Acute coronary syndrome (ACS)
✅Decreases heart rate and myocardial oxygen demand and increases diastolic filling time of ventricles and coronary arteries
⛔️Should be initiated within the first 24 hours of an ACS unless:
✅Signs of HF
✅Active evidence of hemodynamic instability/ shock
✅Increased risk of cardiogenic shock (SBP < 120 mm Hg, heart rate >110 bpm, or <60 bpm)
🛑Relative contraindications
✅.PR interval greater than 0.24 sec,
✅ 2ndor 3rdd egree heart block,
✅active asthma or reactive airway disease
#American Society of Health-System Pharmacists 2020
✅Decreases heart rate and myocardial oxygen demand and increases diastolic filling time of ventricles and coronary arteries
⛔️Should be initiated within the first 24 hours of an ACS unless:
✅Signs of HF
✅Active evidence of hemodynamic instability/ shock
✅Increased risk of cardiogenic shock (SBP < 120 mm Hg, heart rate >110 bpm, or <60 bpm)
🛑Relative contraindications
✅.PR interval greater than 0.24 sec,
✅ 2ndor 3rdd egree heart block,
✅active asthma or reactive airway disease
#American Society of Health-System Pharmacists 2020
Clinical Notes
برنامج BMJ best practices من أفضل البرامج الطبيه في الممارسه الطبية لطلاب الطب بغض النضر طلاب بوورد، او طلاب الامتياز او الصيدلة السريريه او الصيدله العامه والجميل فيه أنه نستطيع تحميل البيانات واستخدامه دون إنترنت لكن تسكررت الحسابات الاوله الذي فعلته…
السلام عليكم
أعتذر عن التأخير في حساب BMJ لأنه حصلت أشكاليه ولم نستطع فعل عدة حسابات
لكن وفرت اليوم حسابات أن شاء الله تكون مفيده ودائما ما تغلق وإن شاء الله تستفيدوا منها ودعوة تكفي☺️
ركزوا الاستخدام شرحته من قبل في فيديو في القناة ما أحد يدخل يرسل ع الإيميل
الرمز هو نفسها الرابط الموجود أعمل فقط نسخ لصق
الحساب الاول
اسم المستخدم
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كلمة السر
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الحساب الثاني
اسم المستخدم
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كلمة السر
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الحساب الثالث
اسم المستخدم
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كلمة السر
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الحساب الرابع
اسم المستخدم
[email protected]
كلمة السر
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أعتذر عن التأخير في حساب BMJ لأنه حصلت أشكاليه ولم نستطع فعل عدة حسابات
لكن وفرت اليوم حسابات أن شاء الله تكون مفيده ودائما ما تغلق وإن شاء الله تستفيدوا منها ودعوة تكفي☺️
ركزوا الاستخدام شرحته من قبل في فيديو في القناة ما أحد يدخل يرسل ع الإيميل
الرمز هو نفسها الرابط الموجود أعمل فقط نسخ لصق
الحساب الاول
اسم المستخدم
[email protected]
كلمة السر
https://www.tg-me.com/+NcBrg4KEj3YwYjQ0
الحساب الثاني
اسم المستخدم
[email protected]
كلمة السر
https://www.tg-me.com/+NcBrg4KEj3YwYjQ0
الحساب الثالث
اسم المستخدم
[email protected]
كلمة السر
https://www.tg-me.com/+NcBrg4KEj3YwYjQ0
الحساب الرابع
اسم المستخدم
[email protected]
كلمة السر
https://www.tg-me.com/+NcBrg4KEj3YwYjQ0
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Clinical Notes
قناة طبية تهدف إلى نشر وتقديم ملاحظات سريرية مهمة وحديثة حول الدواء والتشخيص والمعالجة حسب الجايدلاينات العالمية.
Clinical notes about drug and medicine according to new guidelines and updates.
Clinical notes about drug and medicine according to new guidelines and updates.
🛑Should not fast
✅Poorly controlled hypertension (as defined by your specialist)
✅ Recent acute coronary syndrome / myocardial infarction (<6 weeks)
✅ Hypertrophic Cardiomyopathy with obstruction
✅ Severe valvular disease
✅ Severe heart failure without advanced features
✅ Poorly controlled arrhythmias (as defined by your specialist)
✅ High risk of fatal arrhythmias (e.g. inherited arrhythmic syndromes, arrhythmogenic cardiomyopathy)
✅ Implantable cardioverter defibrillator +/- cardiac resynchronisation therapy
✅Poorly controlled hypertension (as defined by your specialist)
✅ Recent acute coronary syndrome / myocardial infarction (<6 weeks)
✅ Hypertrophic Cardiomyopathy with obstruction
✅ Severe valvular disease
✅ Severe heart failure without advanced features
✅ Poorly controlled arrhythmias (as defined by your specialist)
✅ High risk of fatal arrhythmias (e.g. inherited arrhythmic syndromes, arrhythmogenic cardiomyopathy)
✅ Implantable cardioverter defibrillator +/- cardiac resynchronisation therapy
رمضان كريم وشهر مبارك على سكان غزه وشعب فلسطين الحر الأبي المجاهد كبيرهم وصغيرهم نسائهم ورجالهم وعلى مقاومتة ومجاهديه الشرفاء من استقبلوه بذروة سنام الإسلام،
وعلى المقاومة في لبنان واليمن والعراق وعلى الأمه العربية والإسلاميه وجعله الله شهر خير وبركه ونصراً من الله عزيز
وسلاماً ورحمةٌ من الله على الشهداء الأحرار من وهبوا أجسادهم خالصه لله وفي سبيل الله.
وعلى المقاومة في لبنان واليمن والعراق وعلى الأمه العربية والإسلاميه وجعله الله شهر خير وبركه ونصراً من الله عزيز
وسلاماً ورحمةٌ من الله على الشهداء الأحرار من وهبوا أجسادهم خالصه لله وفي سبيل الله.
🛑Antibotic in acute bronchitis
✅In the UK, NICE recommends antibiotics only in patients who are systemically unwell or at a higher risk of complications. Patients who are at higher risk of complications include
✅People with a pre-existing comorbidity (e.g., significant renal, hepatic, cardiac, respiratory, or neuromuscular disease, immunosuppression)
🛑Patients aged ≥80 years with one or more of the following, or patients aged ≥65 years with two or more of the following:
✅Hospitalisation in the past year
✅Current oral corticosteroid use
✅Type 1 or type 2 diabetes mellitus
✅History of congestive heart failure.
#bmj
✅In the UK, NICE recommends antibiotics only in patients who are systemically unwell or at a higher risk of complications. Patients who are at higher risk of complications include
✅People with a pre-existing comorbidity (e.g., significant renal, hepatic, cardiac, respiratory, or neuromuscular disease, immunosuppression)
🛑Patients aged ≥80 years with one or more of the following, or patients aged ≥65 years with two or more of the following:
✅Hospitalisation in the past year
✅Current oral corticosteroid use
✅Type 1 or type 2 diabetes mellitus
✅History of congestive heart failure.
#bmj
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هذه القناة توفر لكم العديد من الوصفات الطبية الأكثر إنتشار في اليمن والتي يصل عددها اكثر من 10,000 وصفه مع توضيح اسم الدواء وصورة الدواء التي تساعدك في التطبيق عن بُعد وكذلك للطلاب والطالبات الذي ليس لهم القدرة على
النزول الميداني للصيدليات
اسال الله ان يكتب لنا الاجر ونشكر طلابنا في الجامعه الامارتيه الي جمعوها و اخذوها كتدريب ميداني عليهم وانا كنت المشرف التدريب
🛑سيتم نشر 5-10 وصفات طبية يومياً
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النزول الميداني للصيدليات
اسال الله ان يكتب لنا الاجر ونشكر طلابنا في الجامعه الامارتيه الي جمعوها و اخذوها كتدريب ميداني عليهم وانا كنت المشرف التدريب
🛑سيتم نشر 5-10 وصفات طبية يومياً
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قناة الوصفات الطبية الخاصه للبروف د.مختار الغرافي الجامعه الامارتية💊
هذه القناة توفر لكم العديد من الوصفات الطبية الأكثر إنتشار في اليمن والتي يصل عددها اكثر من 10.000 وصفه مع توضيح اسم الدواء وصورة الدواء التي تساعدك في التطبيق عن بُعد وكذلك للطلاب والطالبات الذي ليس لهم القدرة على
النزول الميداني للصيدليات.
النزول الميداني للصيدليات.
الرمز الجديد لحساب لكزيكمب
New Lexicomp account
For the website
Username: EHC2024
Password: Lexicomp24!
New Lexicomp account
For the website
Username: EHC2024
Password: Lexicomp24!
KDIGO-2024-CKD-Guideline-Executive-Summary (1).pdf
868.6 KB
Executive summary of the KDIGO 2024 Clinical
Practice Guideline for the Evaluation and
Management of Chronic Kidney Disease: known
knowns and known unknowns
Practice Guideline for the Evaluation and
Management of Chronic Kidney Disease: known
knowns and known unknowns
#remember
✅ All SGLT2i have shown evidence of benefit for HF and CKD.
✅SGLT2i with evidence of ASCVD benefit: canagliflozin, dapagliflozin, and empagliflozin.
✅SGLT2i have decreasing glycemic efficacy as eGFR declines, particularly with eGFR <45 mL/min/1.73 m2, and in this setting, an additional agent may be necessary to achieve glycemic goals.
#UpTodate2024
✅ All SGLT2i have shown evidence of benefit for HF and CKD.
✅SGLT2i with evidence of ASCVD benefit: canagliflozin, dapagliflozin, and empagliflozin.
✅SGLT2i have decreasing glycemic efficacy as eGFR declines, particularly with eGFR <45 mL/min/1.73 m2, and in this setting, an additional agent may be necessary to achieve glycemic goals.
#UpTodate2024